Related Terms

  • Antimony trisulfide, aromatic USP 14, arsenic sulfide, berberis root, bloodroot, buckthorn bark, burdock, cascara, licorice, pokeroot, prickly ash bark, red clover, stillingia root, sulfur, talc, trichloroacetic acid, zinc chloride.

Background

    Evidence Table

      Disclaimer

      These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

      C – C


      C – C

    *Key to grades:

    Tradition

      Disclaimer

      The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.

    Dosing

      Disclaimer

      The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

    • Adults (18 years and older)

      • No specific doses can be recommended, either based on human use or scientific study.
    • Children (younger than 18 years)

      • There is a lack of reliable scientific evidence to support the safe or effective use of the Hoxsey formula in children.

    Safety

      Disclaimer

      The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

    • Allergies

      • Allergy/hypersensitivity to burdock root, potassium iodide, licorice, red clover, stillingia root, berberis root, pokeroot, cascara, prickly ash bark, and buckthorn bark (which all may be contained in the oral Hoxsey tonic) may cause an allergic reaction.
    • Side Effects and Warnings

      • Well-designed safety studies of the Hoxsey formula are currently unavailable. It is not known if concentrations of the various ingredients are great enough to cause side effects that may be associated with those ingredients when used alone in therapeutic amounts.
    • Pregnancy and Breastfeeding

      • There is a lack of reliable scientific study of the Hoxsey formula in pregnant or breastfeeding women. Safety is unknown, and therefore use cannot be recommended.

    Interactions

      Disclaimer

      Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

    • Interactions with Drugs

      • There is a lack of published scientific evidence available of drug interactions with the Hoxsey formula. It is not known if concentrations of the various ingredients are great enough to cause interactions that may be associated with those ingredients when used alone in therapeutic amounts. The formula may include administration of antimony trisulphide, Aromatic USP 14, arsenic sulfide, berberis root, bloodroot, buckthorn bark, burdock, licorice, pokeroot, cascara, potassium iodide, prickly ash bark, red clover, stillingia root, sulfur, talc, trichloroacetic acid, and/or zinc chloride.
    • Interactions with Herbs and Dietary Supplements

      • Scientific evidence of herb or supplement interactions with the Hoxsey formula is currently unavailable. It is not known if concentrations of the various ingredients are great enough to cause interactions that may be associated with those ingredients when used alone in therapeutic amounts. The formula may include administration of antimony trisulphide, Aromatic USP 14, arsenic sulfide, berberis root, bloodroot, buckthorn bark, burdock, licorice, pokeroot, cascara, potassium iodide, prickly ash bark, red clover, stillingia root, sulfur, talc, trichloroacetic acid, and/or zinc chloride.

    Attribution

    • This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration ().

    Bibliography

      Disclaimer

      Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

    • Austin S, Baumgartner E, DeKadt S. Long term follow-up of cancer patients using Contreras, Hoxsey and Gerson therapies. J Naturopathic Med 1995; 5(1):74-76.
    • Gebland H. The hoxsey treatment. Unconventional Cancer Treatments. Washington, DC: U.S. Government Printing Office, 1990:75-81.
    • Hartwell JL. Plants used against cancer. A survey. Lloydia 1971;34(1):103-160.
      View Abstract
    • Morton JF. Medicinal plants–old and new. Bull Med Libr Assoc 1968;56(2):161-167.
      View Abstract